A PATIENT WITH TUBERCULOUS LYMPHADENITIS COMPLICATING INTERFERON BASED HEPATITIS C THERAPY
Abstract
Interferon therapy, which remains a
backbone of Hepatitis C treatment, is potentially
immunosuppressive (1) and can
predispose to infections (2). The association
between Interferon and tuberculosis
is not well described. We herein report a
case of tuberculous lymphadenitis complicating
Interferon therapy given for
chronic Hepatitis C infection.
Keyword :Hepatitis C, Tuberculosis, Interferon,
Ribavirin
Full Text:
PDFReferences
Beq S, Rozlan S, Pelletier S, Willems B,
Bruneau J, Lelievre J-D, et al. Altered
Thymic Function during Interferon Therapy
in HCV-Infected Patients. Grossman Z,
editor. PLoS ONE. 2012 Apr 16;7
(4):e34326.
Antonini MG, Babudieri S, Maida I, Baiguera
C, Zanini B, Fenu L, et al. Incidence
of Neutropenia and Infections During Combination
Treatment of Chronic Hepatitis C
with Pegylated Interferon Alfa-2a or Alfa-2b
Plus Ribavirin. Infection. 2008 May 3;36
(3):250–5.
Payer BA, Reiberger T, Breitenecker F,
Aichelburg MC, Schuster C, Heil PM, et al.
The risk of infections in HIV-HCV coinfected
patients during antiviral therapy with
pegIFN+RBV. J. Infect. 2012 Aug;65
(2):142–9.
Killingley B, Bhagani S, Slapak G, Yee
TT, Johnson M. Tuberculosis complicating
treatment of hepatitis C in an HIV-infected
haemophilia A patient. Haemophilia. 2006
Sep;12(5):545–7.
Pérez Elías MJ, Miguel LG, García JG,
Ramírez MLM, Muriel A, Machín Lázaro
JM, et al. Tuberculosis Complicating Hepatitis
C Treatment in HIV Infected Patients.
Clinical Infectious Diseases. 2009 Apr
;48(8):e82–e85.
Sabbatani S, Manfredi R, Marinacci G,
Pavoni M, Cristoni L, Chiodo F. Reactivation
of severe, acute pulmonary tuberculosis
during treatment with pegylated interferon-
alpha and ribavirin for chronic HCV
hepatitis. Scand. J. Infect. Dis.
;38(3):205–8.
Farah R, Awad J. The association
of interferon with the development
of pulmonary tuberculosis. Int
J Clin Pharmacol Ther. 2007
Nov;45(11):598–600.
Tsai M-C, Lin M-C, Hung C-H.
Successful Antiviral and Antituberculosis
Treatment With Pegylated
Interferon-alfa and Ribavirin in a
Chronic Hepatitis C Patient With
Pulmonary Tuberculosis. Journal
of the Formosan Medical Association.
Sep;108(9):746–50.
Babudieri S, Soddu A, Murino M,
Molicotti P, Muredda AA, Madeddu
G, et al. Tuberculosis Screening
before Anti–Hepatitis C Virus Therapy
in Prisons. Emerging Infectious
Diseases . 2012 Apr;18(4).
A v a i l a b l e f r o m : h t t p : / /
wwwnc.cdc.gov/eid/article/18/4/11-
_article.htm
Belkahla N, Kchir H, Maamouri
N, Ouerghi H, Hariz FB, Chouaib
S, et al. Reactivation of tuberculosis
during dual therapy with pegylated
interferon and ribavirin for
chronic hepatitis C. Rev Med Interne.
Nov;31(11):e1–3.
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An initiative of The Tamil Nadu Dr M.G.R. Medical University