IgG4 related sclerosing disease - a case report

Abstract

IgG4 related sclerosing disease is an immune mediated disorder that affects multiple systems. This disorder is characterized by elevated serum IgG4 levels, IgG4 rich lymphoplasmacytic infiltration of various organs and typical imaging features that have since been described in  literature.IgG4 related sclerosing disease is characterised by IgG4 positive plasma cell infiltration of various target organs resulting in fibrosis of the involved organs.Autoimmune  pancreatitis of lymphoplasmacytic type is one of the most common manifestations of this disease. In this paper, we present a case report of a 66 year old lady who presented with pyrexia of unknown origin and low grade obstructive jaundice who on imaging was discovered to have features of autoimmune pancreatitis in addition to other imaging features of IgG4 disease as described in literature