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RARE CASE REPORT-METAPLASTIC CARCINOMA OF BREAST WITH MESENCHYMAL DIFFERENTIATION (CHONDROID AND OSTEOID)

ANITA KUMARI CHANDRASEKARAN

Abstract


Metaplastic carcinoma of the breast is a rare         subtype of breast cancer, which is characterized by estrogen receptor ,progesterone receptor and HER2 negativity         accounting for 0.2 to 1 of breast malignancy. Most reports divide metaplastic carcinomas into two broad categories those that show squamous differentiation and those that    feature       heterologous elements, such as cartilage, bone, muscle, adipose tissue, vascular elements, and even  melanocytes.

 


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References


Rauf F, Kiyani N, Bhurgni Y. Metaplastic carcinoma of breast, an intriguing rarity. Asian Pac J Cancer Prev.2006;7(4): 667-71.

Patrikar A, Maimoon S, Mahore S, Akhtar MA, Wilkinson A. Metaplastic carcinoma of breast (carcinosarcoma variant):a case report. Indian J Pathol Microbiol 2007; 50(2): 396-98.

Gogas J, Kouskos E, Markopoul C, Mantas D et al.Carcinosarcoma of the breast ; report of two cases.Eur J Gynaecol Oncol 2003; 24(1): 93-95.

Juan R (ed). Rosal & Ackerman’s, Surgical Pathology. The Breast. Vol. 2, 9th ed. Mosby, 2004.pp. 1763-876

Image source from New Insights into the Regulation of Epithelial–Mesenchymal Transition by KangAe Lee and Celeste M. Nelson 2009.


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