RARE CASE REPORT-METAPLASTIC CARCINOMA OF BREAST WITH MESENCHYMAL DIFFERENTIATION (CHONDROID AND OSTEOID)
Abstract
Metaplastic carcinoma of the breast is a rare subtype of breast cancer, which is characterized by estrogen receptor ,progesterone receptor and HER2 negativity accounting for 0.2 to 1 of breast malignancy. Most reports divide metaplastic carcinomas into two broad categories those that show squamous differentiation and those that feature heterologous elements, such as cartilage, bone, muscle, adipose tissue, vascular elements, and even melanocytes.
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Image source from New Insights into the Regulation of Epithelial–Mesenchymal Transition by KangAe Lee and Celeste M. Nelson 2009.
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