CUTANEOUS POLYARTERITIS NODOSA WITH EARLY DIGITAL GANGRENE, SALVAGED WITHOUT AMPUTATION A CASE REPORT
Abstract
Cutaneous polyarteritis nodosa (CPAN) is an uncommon form of vasculitis involving small and medium sized arteries of unknown aetiology. The disease can be differentiated from polyarteritis nodosa by its limitation to the skin and lack of progression to visceral involvement. The characteristic manifestations are subcutaneous nodule, livedo reticularis, and ulceration, mostly localized on the lower extremities. We present a case of 6 years old girl presented with subcutaneous nodules, livedo reticularis, and early gangrenous changes of both index fingers, without systemic manifestations. Occurrence of gangrene is an unusual initial manifestation of CPAN. Salvage of gangrenous finger without amputation is very rare.Therapy with Methyl prednisolone, Nicoumalone, Methotrexate produced a marked improvement, patient discharged and on regular follow up.
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Crowson AN, Mihm MC, Jr, Magro CM. Cutaneous vasculitis: a review. J Cutan Pathol.2003;30:161–173.
Daoud MS, Hutton KP, Gibson LE. Cutaneous periarteritis nodosa: a clinicopathological study of 79 cases. Br J Dermatol. 1997;136:706–713.
Seung Won Choi et al. Cutaneous Polyarteritis Nodosa Presented with Digital Gangrene: A Case Report. J Korean Med Sci. 2006 April; 21(2): 371–373.
Bauza A, Espana A, Idoate M. Cutaneous polyarteritis nodosa. Br J Dermatol. 2002;146:694–699] .
Kumar L,ThapaBR,SarkarB.Benign cutaneous polyarteritis nodosa in children below 10 years of age- a clinical experience.Ann Rheum Dis 1995;54:134-136.
Mat C,Yurdakul S, Tuzuner N,Tuzun Y.Small vessel vasculitis and vasculitis confined to skin.Baillieres Clin Rheumatol 1997;11:237-257.
Till SH, Amos RS. Long-term follow-up of juvenile-onset cutaneous polyarteritis nodosa associated with
streptococcal infection. Br J Rheumatol. 1997;36:909 – 911.
Albornoz MA, Benedetto AV, Korman M, McFall S, Tourtellotte CD, Myers AR. Relapsing cutaneous
polyarteritis nodosa associated with streptococcal infections. Int J Dermatol. 1998;37:664–666.
. 9. Stussi G, Schneider E, Trueb RM, Seebach JD. Acral necrosis of the fingers as initial manifestation of cutaneous
polyarteritis nodosa. Angiology. 2001;52:63–67.
Dewar CL, Bellamy N. Necrotizing mesenteric vasculitis after long-standing cutaneous polyarteritis nodosa. J Rheumatol. 1992;19:1308–1311.
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