A RARE CAUSE OF GENERALISED LYMPHADENOPATHY
Abstract
Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai- Dorfman syndrome is a rare benign proliferative histiocytic disease of unknown origin. It predominantly affects the lymph nodes. The head and neck region usually in association with lymph node involvement represents one of the most common extra nodal areas affected by SHML. The other common extra nodal site is skin.Rarely, there is wide spread dissemination with liver, kidney, respiratory organs, orbit, and eyeball involvement. The mean age of onset is 20 years (birth to 74 years).
Full Text:
PDFReferences
Das DK, Gulati A, Bhatt NC, Sethi RG. Sinus histiocytosis
with massive lymphadenopathy (Rosai Dorfman Disease): Report of two cases with fine needle aspiration cytology.Diagn Cytopathol 2001; 24 : 42-45
TS Tiong, G.K.Swethadri, S.K.Subramaniam; RosaiDorfman Disease A case report. Internet J Otorhinolaryngology, 2007
Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy: A pseudolymphomatous benign disorder. Analysis of 34 cases. Cancer 1972; 30: 1174-88
Jani PA, Banjan D. A case of Sinus Histiocytosis with Massive Lymphadenopathy ( Rosai- Dorfman Syndrome ) from Western India. Mcgill J Med 2008 11(2):156-59
Kushwaha R, Ahluwalia C, Sipayya V. Diagnosis of SinusHistiocytosis with massive lymphadenopathy ( RosaiDorfman Disease) by fine needle aspiration cytology.J Cytol 2009; 26(2): 83-85
S Bist, Manisha Bisht, S Varshney, VP Pathak; rosai Dorfman Syndrome with Extranodal Manifestation; http://www.japi.org/june 2007/CR-445.htm.Accessed on 2010
Kumar B, Karki S, Paudyal P. Diagnosis of Sinus histiocytosis with massive lymphadenopathy (RosaiDorfman disease) by fine needle aspiration cytology. Diagn Cytopathol 2008; 36: 691-95
DeshpandeAH, Nayak S, Munshi MM. Cytology of Sinus histiocytosis with massive lymphadenopathy (RosaiDorfman disease). Diagn Cytopathol 2000; 22 :181-85
Rosai J. Lymph Nodes; Rosai and Ackerman's Surgical Pathology; 9th ed. New York; Mosby 2004 Vol 2.pp.1911-13
Sennes L, Koishi H, Cahali R, Sperandio F, Butugan O. Rosai Dorfman disease with extranodal manifestation in the head. Ear Nose Throat J 2004; 83 (12) : 844-47
Foucar E, Rosai J, Dorfman RE. Sinus Histiocytosis with massive lymphadenopathy:an analysis of 14 deaths occurring in a patient registry. Cancer 1984; 54: 1834-40.
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An initiative of The Tamil Nadu Dr M.G.R. Medical University