TREATMENT OUTCOME IN CUTANEOUS BASAL AND SQUAMOUS CELL CARCINOMAS

Abstract

Objective-To analyze retrospectively the
outcome in patients with squamous cell
carcinoma (SCC) and basal cell carcinoma
(BCC) of skin, at our institute. Materials
and methods-A total of 168 patients
had reported with primary skin malignancies
to our institute from 2005 to
2008. Of these, 40 patients (23.8) had
BCC and 77 (45.8) had SCC. The predominant
age group was fifth decade for
both malignancies. While BCC had equal
incidence in either sex, SCC was predominantly
seen in males. Radiotherapy
was the predominant treatment modality
for patients with BCC, 20 patients treated
with radiotherapy, 16 with wide excision
and 4 with excision followed by radiotherapy.
For squamous cell carcinoma, wide
excision was done in 41 patients, amputation
in 21 patients, radiotherapy in 9
patients and excision followed by radiotherapy
in 6 patients. Radiotherapy was
given mainly with 4 and 9 MeV electrons.
All patients were followed up to November
2009. Results-All patients with basal
cell carcinoma are currently disease free.
All patients with squamous cell carcinoma
who received radiotherapy, either alone or
following wide excision are disease free. 39
out of 41 patients treated by wide local excision
and 17 out of 21 amputated patients
are disease free. One patient died due to
non-malignant cause and the remaining
due to disease. There was no significant
difference in survival on comparing both
groups.Conclusion - Radiotherapy is quite
effective in the management of cutaneous
BCC and SCC.