Foot drop in a renal transplant recipient A case report and review of literature
Abstract
Tacrolimus is a potent immunosuppressive
agent used in solid organ transplantation.
it acts by inhibiting calcineurin
phosphatase and inhibits T-lymphocyte
activation. Neurotoxicity is a potentially
serious toxic effect of tacrolimus which
often is under-recognised. Neurotoxicity
ranges from tremors and insomnia to seizures
and encephalopathy.We describe
a 46 yr-old male renal transplant recipient
who developed right foot drop after 6
months of renal transplantation due to
tacrolimus toxicity which improved after
tacrolimus dose reduction.
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