Hemolytic Uremic Syndrome- An unusual complication of snake envenomation
Abstract
Snake envenomation is an important and
common cause of acute kidney injury
(AKI) in India. The incidence of AKI following
snake bite in India is 13-32 percent.
It accounts for 1,50,000 deaths
every year all over the world. AKI can
occur following bites from snakes belonging
to Elapidae, Viperidae and Colubridae
families, due to multiple mechanisms
such as hemodynamic disturbances,
direct tubular toxicity, coagulopathy,
hemoglobinuria and myoglobinuria.
Hemolytic Uremic Syndrome (HUS)
is an unusual cause of AKI following
snake envenomation. We are reporting
case series of two patients who developed
HUS following snake envenomation
and improved after treatment with therapeutic
plasma exchange (TPE). HUS
complicating snake bite has been reported
earlier but those patients were not
offered therapeutic plasma exchange.
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