A CASE OF CHORONIC IDIOPATHIC MYELOFIBROSIS
Abstract
Abstract :
Idiopathic myelofibrosis is a chronic clonal myeloid disorder characterized by anemia, splenomegaly, immature granulocytes, erythroblasts, and teardrop-shaped red cells in the blood, marrow fibrosis, and osteosclerosis. Myelofibrosis with myeloid metaplasia and idiopathic myelofibrosis currently are the two most frequently used terms for the disease. Idiopathic myelofibrosis characteristically occurs after age 50 years.The median age at diagnosis is approximately 65 years. The incidence of the disease is approximately 0.5-1.5 cases per 1,00,000 per year and a median age of onset of 67 years.Here we are presenting this patient 62 years old male,farmer by occupation, who was admitted in our hospital with massive splenomegaly.
Keyword :Myelofibrosis,splenomegaly,tear drop cells,marrow fibrosis,JAK2 mutation
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