AN UNSUAL CASE OF SPLENOMEGALY WITH POLYARTHRITIS
Abstract
Abstract : Massive splenomegaly is defined as spleen pal pable more than 8cm below the left costal margin or its drained Weight more than 1000g. 1Myelofibrosis is one of the rare causes of massive splenomegaly. Idiopathic myelofibrosis is being mentioned as a rare disease in the Office of Rare Diseases (ORD) by National Institute of Health (NIH). Even rarer is the presentation of myelofibrosis with polyarthritis. 5 Extramedullary haematopoiesis involving the synovium is encountered in myelofibrosis patients with myeloid metaplasia.We encountered one such situation in a 42 year old male, who presented with abdominal fullness,polyarthritis, pruritic rash and weight loss, which later turned out to be a case of myelofibrosis with polyarthritis
Keyword : MYELOFIBROSIS, POLYARTHRITIS, SPLENOMEGALY, BONE MARROW
Full Text:
PDFReferences
; Drew Provan et .al. .IDIOPATHIC MYELOFIBROSIS ;Oxford Handbook of Clinical Haematology Second edition; Published in the United States by oxford university press ;2004;(p256-260)
Jerry L .Spivak;Polycythemia Vera and Other Myeloproliferative Diseases; Dr. Fauci's and Dr.
Longo et al. HARRISON’S PRINCIPLES OF MEDICINE [18 TH EDITION]; USA;The McGraw-Hill Companies.2012(p898-904)
MARK H. HEINICKE, MOHAMMAD H. ZARRABI, And PETER D. GOREVIC; Arthritis due to synovial involvement by extramedullary haematopoiesis in myelofibrosis with myeloid metaplasia; Annals of the Rheumatic Diseases, 1983, 42, 196-200
BAROSI et al ; ERYTHROKINETIC CLASSIFICATION OF MYELOFIBROSIS;British journal of hematology;1981
Marshall A. Lichtman, Thomas J. Kipps, Uri Seligsohn, Kenneth Kaushansky, Josef T. Prchal; Myelodysplastic Syndromes; WILLIAM’s TEXT BOOK OF HEMETOLOGY [ 8th edition];2010;USA;The Tata Mcgraw Hill Companies.(p1018-p1025)
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An initiative of The Tamil Nadu Dr M.G.R. Medical University