POLYCYTHEMIA VERA PRESENTING AS SPLENIC INFARCT
Abstract
Polycythemia vera is most often recognized
by the incidental discovery of a
high hemoglobin or hematocrit. In about
20 of patients it presents with thrombotic
complications. We are presenting one
such case where polycythemia vera
manifested itself as splenic infarct due to
splenic vein thrombosis.A 49 year old
female presented with left sided abdominal
pain, mild fever and easy fatiguability
of 10 days duration. Imaging showed
splenic vein thrombosis with splenic infarct.
Hematological evaluation revealed
increased hemoglobin, leucocytosis and
thrombocytosis. Further investigations
showed decreased erythropoietin and
JAK2 mutation positivity. A diagnosis of
polycythemia vera with splenic infarct
due to splenic vein thrombosis was made
and she was treated with phlebotomy.
Full Text:
PDFReferences
Spivak JL. Polycythemia vera and
myeloproliferative diseases. In:
Braunwald E, Hauser SL, Fausi AS,
Casper DL, editors. Harrisons Principles
of Internal Medicine. 18th ed.
New York:McGraw-Hill; 2001. pp. 671
–674.
Stephen J.McPhee- Current medical
Diagnosis & Treatment 2011
pp.489-490.
Stephen O.Ciurea and Ronald Hoffman
-Oxford textbook of medicine;
pp.4264-4273.
Downer W, Peterson S- Massive
splenic infarction and liquefactive necrosis
complicating polycythemia
vera. AJR Am J Roentgenol
;161:79–80
Gumina RJ, Foley DA, Tefferi A.
Polycythemia vera—a case report
and discussion on pathogenic mechanisms
of increased thrombosis. Angiology
;53:587 to 589
Peter P. Tóth, MD, PhD; Robert K.
Reuter, DO; James. Spontaneous
Splenic infarction secondary to Diabetes
Induced Microvascular Disease-
Arch Fam Med. 2000;9:195-197
D Beckett,C Miller,JR Ferrando,AK
Banerjee.Polycythemia vera presenting
as massive splenic infarction and
liquefaction.British Journal of Radiology(
77:876-877.
S Parija,M M Mahopatra& BK Pattnaik.
Indian Journal Ophthalmol 2008
Jul-Aug,56(4)327-329.
Hari,Shadan.Diagnosis of polycythemia
vera in an anemia patient.South Med
Journal 2000;93(7).
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An initiative of The Tamil Nadu Dr M.G.R. Medical University