Cyto-Histopathological Diagnosis of Salivary Duct Carcinoma of Parotid Gland– A Rare Case Report
Abstract
Salivary duct carcinoma is defined as “an aggressive adenocarcinoma that resembles high grade breast ductal carcinoma”. It was originally described by Kleinsasser et al in 1968. Salivary duct carcinomas represent only 0.2% of all epithelial salivary gland neoplasms with the most common site being the parotid gland. It can occur de novo or as the malignant component in carcinoma ex pleomorphic adenoma. The tumor usually presents as rapidly enlarging parotid mass associated with facial nerve palsy in 42% of cases, pain in 23% and cervical lymphadenopathy in 35% of cases. Here we report the cytohistopathological and Immunohistochemical diagnosis of salivary duct carcinoma in a 65 year old female presenting as a painful left parotid swelling with left facial nerve palsy
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