Unusual Presentation of Tuberculosis
Abstract
Hemophagocytic lymphohistiocytosis (HLH) covers a wide array of related life-threatening conditions featuring ineffective immunity characterized by an uncontrolled hyper inflammatory response. HLH is often triggered by infection. Though it was under diagnosed earlier now it is increasingly being diagnosed across the world. Laboratory parameters like Ferritin, triglycerides and fibrinogen along with bicytopenia/pancytopenia aid in confirmation of this diagnosis. Bone marrow may or may not show evidence of HLH. Hence absence of involvement should not exclude the diagnosis of HLH. HLH complicating tuberculosis is a very rare entity. Management is largely based on HLH-2004 protocol. Almost all cases of primary HLH require Hematopoietic Stem Cell transplantation after initial treatment with HLH 2004 protocol. Here we report a case of a 49yr old male with HLH secondary to Tuberculosis.
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