Schizophrenia like Psychotic Illness in A Patient with Megalencephalic Leucoencephalopathy with Subcortical Cyst
Abstract
Megalencephalic Leukoencephalopathy with subcortical Cyst (MLC) is a progressive neurodegenerative disorder with most cases considered to be autosomal recessive in nature with the gene locus on chromosome 22q13.3. The disorder presents with developmental delay, intellectual disability, seizures, ataxia, spasticity, extra pyramidal symptoms, tics, athetosis and macrocephaly. Psychiatric symptoms such as depression and obsessive-compulsive behavior have been reported in patients with this disorder. We report a case of a patient with MLC who presented with an episodic psychotic illness.
Full Text:
PDFReferences
Gangadhar K, Patwari S, Verma A, Kaviyarasy -.Megalencephalic Leukoencephalopathy with Subcortical Cyst: A Case Report. Nepal J Radiol. 2013 Mar 3;2(2):76–80. Available from: https://www.nepjol.info/index.php/NJR/article/view/7691
Singhal B, Gorospe J, Naidu S. Megalencephalic leukoencephalopathy with subc. [J Child Neurol. 2003] - Pub-Med - NCBI. J Child Neurol [Internet]. 2003 Sep [cited 2014 Sep 2];18(9). Available from: http://www.ncbi.nlm.nih.gov/ pubmed/14572144
van der Knaap MS, Scheper GC. Megalencephalic Leukoencephalopathy with Subcortical Cysts. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJ, Stephens K, et al., editors. Gene Reviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993 [cited 2018 Jan 6]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1535/
Batla A, Pandey S, Nehru R. Megalencephalic leukoencephalopathy with subcortical cysts: A report of four cases. J Pediatr Neurosci. 2011;6(1):74–7. Availabel from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173924/
Anand KS, Garg J, Valecha Y, Makar RS. Megalencephalic leukoencephalopathy with subcortical cyst. J Indian Acad Clin Med. 2007;8:250–2. Available from: http:// medind.nic.in/jac/t07/i3/jact07i3p250.pdf
Kumar MK, Singh BB. Megalencephalic leukoencephalopathy with subcortical cysts in all three siblings of a non-Aggarwal Indian family. Ann Indian Acad Neurol. 2102 Sep;15(3):214–7. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424803/
Suguira C, Shiota M, Mageaki Y. Late-onset neuropsychological symptoms in a ... [Neuropediatrics. 2006] - PubMed - NCBI. Neuropediatrics. 2007 Oct;37(5):286–90. Avai lable f rom: ht t ps : / /www. nc bi . nlm.nih.gov / pubmed/17236107
Koyama S, Toru K, Arawaka S. A Japanese Adult Case of Megalencephalic Leukoencephalopathy with Subcortical Cysts with a Good Long-term Prognosis. Intern Med. 51:503–6. Available from: https://www.researchgate.net/ publication/24377448_Megalencephalic_leukoencephalopathy _with_subcortical_cysts_in_an_adult
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An initiative of The Tamil Nadu Dr M.G.R. Medical University