A Study on Effect of Severity of Depression on Sleep Architecture in Diabetic Patients
Abstract
Background: Diabetes mellitus is one of the commonest health care problem in India with 13.5% prevalence. Sleep disturbances are common in type 2 Diabetes mellitus. Similarly the prevalence of depression in type 2 diabetes mellitus is 38.75%. Both depression and sleep disturbance are bi directionally related in diabetics and the severity of depression may have an effect on sleep architecture which is the basic hypothesis of our study. Objective: To evaluate the effect of severity of depression on sleep architecture in diabetics. Materials and Methods: A Total of 30 diabetic patients 40-60 years of age were enrolled. Digital Polysomnography was recorded in clinical Physiology research lab, Institute of Physiology and Experimental Medicine, Rajiv Gandhi Government General Hospital. HDRS (Hamilton depression rating scale) of each patient was calculated. Patients were grouped into various categories based on their severity of depression. They were then analysed in relation with sleep timing of different stages and also sleep latency and sleep efficiency. Results: Out of a total 30 patients 53.3% were males while the rest 46.7% were females. The mean age of the patients was 50.83± 5.38 years. Parameters were positively influenced by depression. As the severity of depression increases there is decrease in mean duration of each sleep stage and also the total sleep time and sleep efficiency and similarly there was an increase in sleep latency. Influence of severity of depression on all these parameters was statistically significant with P value less than 0.005. Conclusion: Severity of depression has a positive influence on the sleep architecture in diabetics.
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