Atypical Presentation of Sjogren’s Syndrome-Hypokalemic Periodic Paralysis & Acute Liver Failure

Vignesh S and Tolstoy R .

Abstract


        

          Sjogren’s syndrome is a chronic slowly       progressive autoimmune  disease with a female  predominance (female to male ratio is 9:1).  It is classified in to primary and secondary sjogren’s syndrome. Primary sjogren’s syndrome is commonly associated with extra      glandular  and systemic manifestation with  prevalence of    0.5-1%. Secondary sjogren’s syndrome is present in 30% of people with autoimmune rheumatoid arthritis. Common    presentation of sjogren’s syndrome includes xerostomia,  keratoconjunctivissicca, xerotrachea, esophageal and gastric atrophy & dyspareunia. Here we are presenting a case that presented with recurrent hypokalemic periodic paralysis and acute liver failure and found to have renal tubular acidosis and autoimmune hepatitis, which is not a common presentation of sjogren’s syndrome. Patient improved symptomatically after being treated with steroids and other supportive measures.

 


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References


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