A case report of Wilson’s disease

Uma Maheshwari V S .

Abstract


Wilson’s disease is an autosomal recessive disorder

affecting copper metabolism. It is due to the mutation in

ATP7B gene that codes for ATPase protein which facilitates

the hepatic excretion of copper. Accumulation of copper

affects tissues such as liver, brain, spleen, eyes and kidneys

producing pathological changes resulting in clinical

manifestations. Treatment with D-Penicillamine and Zinc

brings out improvement.

 


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