COMPARATIVE STUDY OF PLAIN BUPIVACAINE vs. BUPIVACAINE WITH ADDITIVE MIDAZOLAM IN SUPRACLAVICULAR APPROACH OF BRACHIAL PLEXUS BLOCK
Abstract
Aim-To compare the efficacy of adding 50 micrograms per kg of midazolam to Bupivacaine hydrochloride in supraclavicular approach of brachial plexus upon the onset of sensory block, duration of sensory block, onset of motor block, duration of motor block and also compare the sedation with that of plain bupivacaine in the same concentration. Methodology-Study was conducted in 60 patients (n60) of ASA I and II .The age group of patients was 20-60 years. Patients were randomly allocated into two groups, Group A and Group B.Group A(n30) was given 40 ml of 0.375 Bupivacaine and Group B(n30) was given 40 ml of 0.375 Bupivacaine with 50micrograms per kg of Midazolam. Results-Post operative analgesia was significantly longer in group B(with midazolam) as compared to group A with P value 0.001. So there was statistically significant difference. Mean duration of motor blockade in group B was also longer than in group A with P value 0.05. Here also there was statistically significant difference. Pain score was significantly low in group B , compared to group A at 12 hours postoperatively. Sedation was assessed using the sedation score described by Culebras et al, with sedation (Sedated, responding to mild physical stimulus) in group B compared to group A (who were awake and alert).Onset of sensory block even though was shorter in group B compared to group A but p value 0.05. So there was no statistically significant difference. Onset of motor block in group B was also shorter in than group A but p value was 0.05 min. So there was no statistically significant difference.
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