Hemolytic diseases of newborn caused by Lewis b antibodies-A case report
Abstract
Hemolytic disease of newborn due to minor blood group incompatibility is rare. It is being detected more often nowadays due to 11 cell panel screening of antibodies and antibody elution technique. Rh isoimmunization is decreasing due to Rh antibody administration. There is only one case report so far of alloimmunization due to Lewis b antibody. Here we report a rare case of Lewis b antibody causing hemolytic disease of newborn which presented as prolonged indirect hyperbilirubinemia with anemia. Neonate was treated with phototherapy, exchange transfusion and intravenous immunoglobulin. Mothers serum confirmed Lewis b antibody reacting at 37 C thus clinically significant causing hemolytic disease of newborn.
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