Case Series on L Asparginase induced Cortical Venous Thrombosis in Acute Lymphoblastic Leukemia.
Abstract
L- Asparginase has become an integral
part in treatment protocols of Acute Lymphoblastic
leukemia. It has shown to improve
outcome in these patients.The major
detrimental side effect of using L Asparginase
is thrombo embolism. Among
these Cortical vein thrombosis is a worrying
complication.We are presenting here
case series of 3 patients who has developed
cortical vein thrombosis during different
phases of treatment for Acute
Lymphoblastic leukemia.All patients were
successfully treated with low molecular
heparin other supportive care and had a
speedy recovery. Early recoginition of
this condition is very important as it is
readily treatable and if not will be life
threatening.
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