A RARE CAUSE OF ACUTE LIVER FAILURE
Abstract
Abstract :
Hepatic involvement in systemic amyloidosis
is common but is rarely symptomatic.
It is usually in the form of hepatomegaly
and asymtomatic elevation in
serum alkaline phosphatase. Hyperbilirubinemia
is rare and signifies worse
prognosis. Hepatic failure due to systemic
amyloidosis is very rare and it can
manifest as acute or subacute liver failure.
We report a case of a 55 year old
man presenting with progressive jaundice
followed within a month by ascites
and encephalopathy. He was diagnosed
as acute hepatic failure and had a rapidly
worsening clinical course with fatal outcome.
The diagnosis of amyloidosis was
made on postmortem liver biopsy.
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