Prevalence of cirrhotic cardiomyopathy
Abstract
Aim To study the frequency of cirrhotic
cardiomyopathy in liver cirrhosis patients
and its correlation with severity of liver
disease.Method This is a case series
study conducted in Department of Digestive
health and Disease, a tertiary care
hospital in Chennai over the period from
july 2012 Oct-2013. First, resting ECG
was done in enrolled cirrhotic patients .
QTc values were calculated and value
0.44 sec were considered as prolonged.
Systolic dysfunction was assessed by
reduced ejection fraction (value 55). Diastolic
dysfunction assessed by reduced
EA ratio (value 1).Cirrhotic cardiomyopathy(
CCM) is diagnosed by presence of
evidence of either systolic or diastolic
dysfunction, together with prolonged
QTc.Results A total of 106 patients were
selected for the study, out of which 96
(90.5) were male and 10 (9.5) were female.
The mean age was 46.5 years
( 10.8 SD). Out of 106 patients 15 (14.2)
belonged to child Pugh A, 21(19.8) to
child-Pugh B and 70(66) in child-Pugh C.
EA ratio 1 in 34(32.1) cases, prolong QT
interval (0.44sec) in 29(27.8), Ejection fraction
(EF) 0. 55 was present in 19(17.9) patients.
Cirrhotic cardiomyopathy was present
in 39(36.7) cases and frequency correlates
directly with severity of liver disease.
There was no significant difference in
frequency of CCM among alcoholics and
non-alcoholics.Conclusion Cirrhotic cardiomyopathy
is present in 36 percent of cirrhotic
patients and significantly more in
child C group. Presence of this clinical entity
may have major impact on prognosis in
these patient.
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