A CASE OF PROSTHETIC VALVE INDUCED HEMOLYTIC ANEMIA
Abstract
Hemolytic anemia arising after cardiac valve replacement was first described in 1954 soon
after corrective valvular surgery became possible. It results from erythrocyte shearing and
fragmentation as the red cells traverse the turbulent flow through or around the prosthetic valve.
Compensated hemolysis can occur with any type of valve prosthesis and can be detected in almost
every patient depending on the type of prosthetic device. We report a case of hemolytic anemia in a
patient with cardiac valve prostheses
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Kloster FE: Diagnosis and management of complications of prosthetic heart valves. Am J Cardiol
, 1975
Garcia MJ, Vandervoort P, Stewart WJ, et al: Mechanisms of hemolysis with mitral prosthetic
regurgitation. J Am Coll Cardiol 27:399, 1996. [PMID: 8557912]
Crexells C, Aerichide N, Bonny Y, et al: Factors influencing hemolysis in valve prosthesis. Am
Heart J 84:161, 1972. [PMID: 5075069]
Demirsoy E, Yilmaz O, Sirin G, et al: Hemolysis after mitral valve repair; a report of five cases and
literature review. J Heart Valve Dis 17:24, 2008. [PMID: 18365565]
Marsh GW, Lewis SM: Cardiac haemolytic anaemia. Semin Hematol 6:133, 1969. [PMID: 5780687]
Kawase I, Matsuo T, Sasayama K, et al: Hemolytic anemia with aortic stenosis resolved by urgent
aortic valve replacement. Ann Thorac Surg 86:645, 2008. [PMID: 18640351]
Sears DA, Crosby WH: Intravascular hemolysis due to intracardiac prosthetic devices. Am J Med
:341, 1965. [PMID: 14332374]
Maraj R, Jacobs LE, Ioli A, Kotler MN: Evaluation of hemolysis in patients with prosthetic heart
valves. Clin Cardiol 21:387, 1998. [PMID: 9631266]
Myhre E, Rasmussen K, Andersen A: Serum lactic dehydrogenase activity in patients with
prosthetic heart valves: A parameter of intravascular hemolysis. Am Heart J 80:463, 1970. [PMID:
Okita Y, Miki S, Kusuhara K, et al: Propranolol for intractable hemolysis after open heart
operation. Ann Thorac Surg 52:1158, 1991. [PMID: 1953141]
Shapira Y, Bairey O, Vatury M, et al: Erythropoietin can obviate the need for repeated heart valve
replacement in high-risk patients with severe mechanical hemolytic anemia: Case reports and
literature review. J Heart Valve Dis 10:431, 2001. [PMID: 11499585]
Ward A, Clissold SP: Pentoxifylline: A review of its pharmacodynamic and pharmacokinetic
properties, and its therapeutic efficacy. Drugs 34:50, 1987. [PMID: 3308412]
Amidon TM, Chou TM, Rankin JS, Ports TA: Mitral and aortic paravalvular leaks with hemolytic
anemia. Am Heart J 125:122, 1993.
Rodgers BM, Sabiston DC Jr: Hemolytic anemia following prosthetic valve replacement.
Circulation 39:155, 1969.
Lam B-K, Cosgrove DM, Bhudia SK, Gillinov AM. Hemolysis after mitral valve repair: mechanisms
and treatment. Ann Thorac Surg 77:191, 2004. [PMID: 14726060]
Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J: Harrison's Principles of
Internal Medicine, 18th Edition. Ch.57. Anemia and Polycythemia. p.454.
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