NEU-LAXOVA SYNDROME A RARE CONGENITAL ANOMALY INVOLVING MULTIPLE SYSTEMS
Abstract
Neu-Laxova syndrome (NLS) is a rare, uniformly lethal congenital disease characterized
by abnormalities of placentation, marked intrauterine growth retardation (IUGR), extreme
microcephaly, marked edema with skin contractures, ichthyosis, cranio facial anomalies, limb
deformities, a spectrum of central nervous system (CNS) developmental defects and unique facial
appearance. The degrees and presence of these findings are variable in reported cases. Therefore
the differential diagnosis includes very different disorders. The majority of cases were stillborn or die
shortly after birth. We are presenting a case of Neu-Laxova syndrome delivered in our hospital.
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