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Primary Bone Lymphoma (PBL) is a relatively uncommon entity. It represents
approximately 5 percent of all non Hodgkin lymphomas (NHLs) and 3 percent of all bone
malignancies. The femur, tibia, and pelvis are the most common skeletal sites involved. It can occur
at any age, with a peak incidence in the fourth and fifth decades. It can mimic other disease
processes, especially infection and at times arthritis if it is in the periarticular area. So, thorough and
prompt investigatory workup is essential for adequate treatment. We discuss the clinical findings,
diagnosis, and treatment in a case of PBL involving the distal femur

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