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MEDIASTINAL WIDENING WITH ISOLATED BULBAR WEAKNESS- A MASQUERADE OF MYASTHENIA GRAVIS

HARIKRISHNAN S

Abstract


Overall incidence of Thymoma is approximately 0.15 per lakh population
per year. Thymoma is usually a begin tumour from anterior mediastinum. About one third of cases
were diagnosed during Myasthenia Gravis evaluation. One third as asymptomatic mass, one third as
obstructive features. Myasthenia Gravis is the common para-neoplastic syndrome associated with
Thymoma. Ocular weakness is most typical and usual presentation with or without limb involvement,
while early or isolated oropharngeal or limb weakness is very rare. Mainstay of treatment of
Thymoma with Myasthenia Gravis is surgical resection with adequate preoperative preparations such
as plasmapheresis or IV Immunoglobulin.

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