Cover Image

RARE CASE REPORT OF DOUBLE MALIGNANCY URETERAL AND BREAST CARCINOMA.

MADHULIKA M

Abstract


Ureteral cancer and breast cancer can occur
individually in many patients. The occurrence of both in the
same patient is a rare phenomenon. A 52-year old
postmenopausal female, diagnosed as a case of Right
Ureteral cancer-T3N0M0 (HPE-Transitional cell carcinoma),
low-grade papillary type, had undergone Right nephrectomy
with bladder-cyst excision on August-2014. She also received
4 cycles of Inj.Gemcitabine and Inj.Cisplatin, following which
she noticed a lump in the Right breast, upper-outer quadrant.
Clinically it was a 4x4cm mass, mobile and non-tender with
axillary fullness. FNAC-smear was positive for malignancy.
Mammogram showed BIRADS-V and was staged as
cT2N0M0. Right Modified radical mastectomy was done in
January-2015, it was pathologically T3N0M0. HPE came as
Infiltrating ductal carcinoma Grade-II. 44 nodes dissected-no
tumor metastasis. Posterior margins-close margins.
Lymphovascular invasion ve. IHC-Triple Negative. This was
followed by 4cycles of FAC and 4cycles of Taxane. PMRT
was planned in two fieldsTangential portals for flap and Single
AP portal for drainage area with tracheal shield and Head of
humerus shield. 50Gy200cGy25 planned and executed
followed by Post-Axillary boost. This case is presented for its
rarity.


Full Text:

PDF

References


Gologan A, Krasinskas A, Hunt J, Thull DL, Farkas L, Sepulveda

AR (Nov 2005). "Performance of the revised Bethesda guidelines

for identification of colorectal carcinomas with a high level of

microsatellite instability". Archives of Pathology & Laboratory

Medicine 129 (11): 1390–7. doi:10.1043/1543-2165(2005)129

:POTRBG]2.0.CO;2. PMID 16253017.

Lynch HT, Shaw MW, Magnuson CW, Larsen AL, Krush AJ (Feb

. "Hereditary factors in cancer. Study of two large midwestern

kindreds". Archives of Internal Medicine 117 (2): 206–12.

doi:10.1001/archinte.117.2.206. PMID 5901552.

Boland CR, Koi M, Chang DK, Carethers JM (2007). "The

biochemical basis of microsatellite instability and abnormal

immunohistochemistry and clinical behavior in Lynch syndrome:

from bench to bedside". Familial Cancer 7 (1): 41–52. doi:10.1007/

s10689-007-9145-9. PMID 17636426.

Lenhard, R. E., Osteen, R. T., & Gansler, T. (Eds.): The

American Cancer Society's Clinical Oncology (2001). The American

Cancer Society, Atlanta, Georgia.

Vasen HF, Watson P, Mecklin JP, et al.: New clinical criteria for

hereditary nonpolyposis colorectal cancer (HNPCC, Lynch

syndrome) proposed by the International Collaborative Group on

HNPCC. Gastroenterology 116.

Yarbro, C. H., Frogge, M. H., Goodman, M., & Groenwald, S. L.

(Eds.): Cancer Nursing: Principles and Practice (2001). Jones and

Bartlett Publishers, Boston, Massachusetts.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An initiative of The Tamil Nadu Dr M.G.R. Medical University