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NEUROENDOCRINE TUMORS IN DECOMPENSATED LIVER DISEASE

ANAND V VADIVEL

Abstract


We report two cases of neuroendocrine
tumors in patients with decompensated
chronic liver disease. Neuroendocrine
tumour in the setting of decompensated
liver disease is a very rare entity thus the
presentation. Patients who had decompensated
chronic liver disease, diagnosed
by clinical, laboratory and imaging
criteria underwent upper gastrointestinal
endoscopy. During endoscopy, polyps
numbering one to numerous were found
in the stomach and duodenum. Biopsy
was taken from polyps and sent for histopathological
examination. Histopathological
examination was suggestive of neuroendocrine
tumor. To confirm the diagnosis,
Immunohistochemistry for neuroendocrine
markers, chromogranin A,
synaptophysin, Leu7, and neuronspecific
enolase was done. After confirmation
with positive immunohistochemistry, metastatic
work-up was done using CECT
abdomen and PET CT scan


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