A CASE REPORT OF EXTRAPONTINE MYELINOLYSIS IN A PATIENT WITH ADDISON'S DISEASE
Abstract
Osmotic demyelination syndrome
can occur as a complication of therapy of chronic
hyponatremia. Isolated extrapontine myelinolysis occurring in
patients with hypoadrenalism has been quoted in the
literature only rarely. Here, we present a patient with addisons
disease who developed extrapontine myelinolysis during his
recovery from his primary illness. He developed features of
basal ganglia involvement as the manifestation of
extrapontine myelinolysis. Our patient developed this
complication when he was treated with iv fluids for his
vomiting and dehydration. He developed parkinsonian
features following the intravenous fluid therapy. The safe rate
of correction of hyponatremia has not been accurately
determined. The prognosis of this condition varies
considerably, either complete recovery or mortality
can occur as a complication of therapy of chronic
hyponatremia. Isolated extrapontine myelinolysis occurring in
patients with hypoadrenalism has been quoted in the
literature only rarely. Here, we present a patient with addisons
disease who developed extrapontine myelinolysis during his
recovery from his primary illness. He developed features of
basal ganglia involvement as the manifestation of
extrapontine myelinolysis. Our patient developed this
complication when he was treated with iv fluids for his
vomiting and dehydration. He developed parkinsonian
features following the intravenous fluid therapy. The safe rate
of correction of hyponatremia has not been accurately
determined. The prognosis of this condition varies
considerably, either complete recovery or mortality
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PDFReferences
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