CASE REPORT- POST RENAL TRANSPLANT HEPATOCELLULAR CARCINOMA
Abstract
Post renal transplant setting is conducive for occurrence of malignancy due to the uninhibited proliferation of oncogenic viruses, lack of immune surveillance and intense immunosuppression. We are reporting a patient who had Hepatitis C virus (HCV) infection pretransplant and underwent successful renal transplantion ,his younger brother being kidney donor. At 8 years post transplant, he developed calculous cholecystitis for which surgery was planned. During that evaluation he was found to have multifocal hepatocellular carcinoma
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Alan Wilkinson et al;Long term post transplantation management and complications., § - History and physical examination to exclude disseminated or localized organ involvement by PTLD (every 3 months during the first year after transplantation, subsequently at yearly intervals). § - Skin examination by dermatologist (every 6 months in high-risk patients, otherwise yearly). § -Ultrasonography or CT scan of the native kidney (at yearly intervals). § -Gynecologic examination, including PAP smear and ultrasonography of female reproductive organs (at yearly intervals).
§ - In selected cases.
- PSA and digital rectal examination (male 50 yr, at yearly intervals).
-Fecal occult blood testing (age 50 yr, at yearly intervals).
- Abdominal ultrasound and serum -fetoprotein levels (in carriers of hepatitis B or C virus).
-Cystoscopy (de novo hematuria, particularly when history of cyclophosphamide treatment
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