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DRUG INDUCED MEMBRANOUS NEPHROPATHY

SENTHILKUMAR R P PANNERSELVAM

Abstract


Membranous Nephropathy (MGN) could
be either idiopathic (primary) or secondary
to systemic autoimmune disease,
chronic infections, malignancy or therapeutic
drugs. We present a 24 year old
Asian lady, diagnosed to have Wilsons
disease and started on D-Penicillamine.
Eighteen months later she presented
with nephrotic proteinuria, benign urinary
sediment, normal blood pressure and
normal serum creatinine. A renal biopsy
was done which revealed Membranous
Nephropathy. The serum M type Phospholipase
A2 receptor antibody was
negative.Though D-Penicillamine induced
MGN is a well known entity, we
are reporting this case because of its rarity


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