A Study on use of potentially inappropriate medications in elderly
Abstract
Objective -The study was done with the aim to find out the extent of drug use in elderly at the outpatient department of a tertiary care hospital and to evaluate inappropriate prescribing in reference to Beers' criteria 2012 .Materials and Methods- A cross sectional study was carried out at the out patient department of a tertiary care hospital. 153 patients above the age of 65 years were randomly included during the study period of six months from May 2012 to December 2012. The data included the patients' demographic and clinical details and the prescription.
Full Text:
PDFReferences
Juurlink DN, Mamdami M, Kopp A et al. Drug-drug interactions among elderly patients hospitalized for drug toxicity. JAMA 2003; 289: 1652.
Goldberg RM, Mabee J, Chan L, Wong S. Drug-drug and drug-disease interactions in the emergency department: analysis of a high-risk population. Am J Emerg Med 1996; 14: 447–50
Mangoni AA, Jackson SHD. Age-related changes in pharmacokinetics and harmacodynamics: basic principles and practical applications. Br J Clin Pharmacol 2003; 57: 6–14
Tinetti M. Preventing falls in elderly persons. New Eng J Med 2003; 348: 42–9.
Gabriel SE, Jaakkimainen L, Bombardier C. Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs: a meta-analysis. Ann Intern Med1991; 115: 787–96.
Routledge PA, O'Mahony MS, Woodhouse KW. Adverse drug reactions in elderly patients. Br J Clin Pharmacol. 2004;57:121–6
Beijer HJ, de Blaey CJ. Hospitalisations caused by adverse drug reactions (ADR): A meta-analysis of observational studies. Pharm World Sci. 2002;24:46–54
Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. Arch Intern Med. 1997;157:1531–6
Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for
potentially inappropriate medication use in older adults: Results of a US consensus panel of experts. Arch Intern Med. 2003;163: 2716–24.]
Van der Hooft CS, Jong GW, Dieleman JP, Verhamme KM, Van der Cammen TJ, Stricker BH, et al. Inappropriate drug prescribing in older adults: The updated 2002 Beers criteria--a populationbased
cohort study. Br J Clin Pharmacol. 2005;60:137–44.
Niwata S, Yamada Y, Ikegami N. Prevalence of inappropriate medication using Beers criteria in Japanese long-term care facilities. BMC Geriatr. 2006;6:1.]
Radosevi N, Gantumur M, Vlahovi-Palcevski V. Potentially inappropriate prescribing to hospitalised patients. Pharmacoepidemiol Drug Saf. 2008;17:733–7.]
Nixdorff N, Hustey FM, Brady AK, Vaji K, Leonard M, Messinger-Rapport BJ. Potentially inappropriate medications and adverse drug effects in elders in the ED. Am J Emerg Med. 2008;26:697–700
Hosia-Randell HM, Muurinen SM, Pitkälä KH. Exposure to potentially inappropriate drugs and drug-drug interactions in elderly nursing home residents in Helsinki, Finland: A cross-sectional study. Drugs Aging. 2008;25:683–92.
Shenoy S. Evaluation of the drug prescribing pattern in elderly patients in tertiary care hospital. Indian J Pharmacol. 2006;38:S90.
Shenoy S.Evaluation of the drug prescribing pattern in elderly patients in tertiary care hospital.Indian J Pharmacol 2006;38:s90.
Fick DM,Waller JL,Maclean JR.Potentially inappropriate medication use in a medicare management population:Association with higher costs and utilization.J Manag Care Pharm
:7:407-13.
Wawruch M,Fialova D,Zikavska M,Wsolova L,Jezova D,Kuzelova M et al.Factors influencing the use of potentially inappropriate medication in older patients in Slovakia.J Clin Pharm Ther 2008;33:381-92.
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An initiative of The Tamil Nadu Dr M.G.R. Medical University